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TRPV1 ligands with hyperthermic, hypothermic and no temperature effects in rats

Transient receptor potential vanilloid 1 (TRPV1) is a multifunctional ion channel playing important roles in a numerous biological processes including the regulation of body temperature. Within distinct and tight chemical space of chromanyl ureas TRPV1 ligands were identified that exhibit distinctiv...

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Detalles Bibliográficos
Autores principales: Gomtsyan, Arthur, McDonald, Heath A, Schmidt, Robert G, Daanen, Jerome F, Voight, Eric A, Segreti, Jason A, Puttfarcken, Pamela S, Reilly, Regina M, Kort, Michael E, Dart, Michael J, Kym, Philip R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843892/
https://www.ncbi.nlm.nih.gov/pubmed/27227030
http://dx.doi.org/10.1080/23328940.2015.1046013