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TRPV1 ligands with hyperthermic, hypothermic and no temperature effects in rats
Transient receptor potential vanilloid 1 (TRPV1) is a multifunctional ion channel playing important roles in a numerous biological processes including the regulation of body temperature. Within distinct and tight chemical space of chromanyl ureas TRPV1 ligands were identified that exhibit distinctiv...
Autores principales: | Gomtsyan, Arthur, McDonald, Heath A, Schmidt, Robert G, Daanen, Jerome F, Voight, Eric A, Segreti, Jason A, Puttfarcken, Pamela S, Reilly, Regina M, Kort, Michael E, Dart, Michael J, Kym, Philip R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843892/ https://www.ncbi.nlm.nih.gov/pubmed/27227030 http://dx.doi.org/10.1080/23328940.2015.1046013 |
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