To not be hot when TRPV1 is not

Induction of hyperthermia emerged as a major side effect impeding the development of antagonists of the transient receptor potential vanilloid-1 (TRPV1) nociceptor. New ligands are now exploiting the complicated pharmacology of TRPV1 to avoid hyperthermia while insights continue to grow regarding th...

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Detalles Bibliográficos
Autor principal: Blumberg, Peter M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Editorial Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843896/
https://www.ncbi.nlm.nih.gov/pubmed/27227019
http://dx.doi.org/10.1080/23328940.2015.1048045
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author Blumberg, Peter M
author_facet Blumberg, Peter M
author_sort Blumberg, Peter M
collection PubMed
description Induction of hyperthermia emerged as a major side effect impeding the development of antagonists of the transient receptor potential vanilloid-1 (TRPV1) nociceptor. New ligands are now exploiting the complicated pharmacology of TRPV1 to avoid hyperthermia while insights continue to grow regarding the mechanistic basis for the action of TRPV1 ligands on thermoregulation.
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spelling pubmed-48438962016-05-25 To not be hot when TRPV1 is not Blumberg, Peter M Temperature (Austin) Editorial Comment Induction of hyperthermia emerged as a major side effect impeding the development of antagonists of the transient receptor potential vanilloid-1 (TRPV1) nociceptor. New ligands are now exploiting the complicated pharmacology of TRPV1 to avoid hyperthermia while insights continue to grow regarding the mechanistic basis for the action of TRPV1 ligands on thermoregulation. Taylor & Francis 2015-05-07 /pmc/articles/PMC4843896/ /pubmed/27227019 http://dx.doi.org/10.1080/23328940.2015.1048045 Text en © 2015 The Author(s). Published with license by Taylor & Francis Group, LLC http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
spellingShingle Editorial Comment
Blumberg, Peter M
To not be hot when TRPV1 is not
title To not be hot when TRPV1 is not
title_full To not be hot when TRPV1 is not
title_fullStr To not be hot when TRPV1 is not
title_full_unstemmed To not be hot when TRPV1 is not
title_short To not be hot when TRPV1 is not
title_sort to not be hot when trpv1 is not
topic Editorial Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843896/
https://www.ncbi.nlm.nih.gov/pubmed/27227019
http://dx.doi.org/10.1080/23328940.2015.1048045
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