PAF is a potent pyrogen and cryogen in rodents, but it does not mediate thermoregulatory responses to bacterial endotoxin

Concordance between lipopolysaccharide and platelet activating factor - mediated events have suggested that the latter likely mediates all effects induced by the former. In this issue of Temperature, Steiner and Romanovsky challenge this notion, showing that while platelet activating factor is a pot...

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Detalles Bibliográficos
Autores principales: Marathe, Gopal K, McIntyre, Thomas M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Editorial Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843932/
https://www.ncbi.nlm.nih.gov/pubmed/27227061
http://dx.doi.org/10.1080/23328940.2015.1096439
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author Marathe, Gopal K
McIntyre, Thomas M
author_facet Marathe, Gopal K
McIntyre, Thomas M
author_sort Marathe, Gopal K
collection PubMed
description Concordance between lipopolysaccharide and platelet activating factor - mediated events have suggested that the latter likely mediates all effects induced by the former. In this issue of Temperature, Steiner and Romanovsky challenge this notion, showing that while platelet activating factor is a potent pyrogenic mediator, the thermoregulatory responses to lipopolysaccharide are instead induced by prostaglandins.
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spelling pubmed-48439322016-05-25 PAF is a potent pyrogen and cryogen in rodents, but it does not mediate thermoregulatory responses to bacterial endotoxin Marathe, Gopal K McIntyre, Thomas M Temperature (Austin) Editorial Comment Concordance between lipopolysaccharide and platelet activating factor - mediated events have suggested that the latter likely mediates all effects induced by the former. In this issue of Temperature, Steiner and Romanovsky challenge this notion, showing that while platelet activating factor is a potent pyrogenic mediator, the thermoregulatory responses to lipopolysaccharide are instead induced by prostaglandins. Taylor & Francis 2015-12-03 /pmc/articles/PMC4843932/ /pubmed/27227061 http://dx.doi.org/10.1080/23328940.2015.1096439 Text en © 2015 The Author(s). Published with license by Taylor & Francis http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
spellingShingle Editorial Comment
Marathe, Gopal K
McIntyre, Thomas M
PAF is a potent pyrogen and cryogen in rodents, but it does not mediate thermoregulatory responses to bacterial endotoxin
title PAF is a potent pyrogen and cryogen in rodents, but it does not mediate thermoregulatory responses to bacterial endotoxin
title_full PAF is a potent pyrogen and cryogen in rodents, but it does not mediate thermoregulatory responses to bacterial endotoxin
title_fullStr PAF is a potent pyrogen and cryogen in rodents, but it does not mediate thermoregulatory responses to bacterial endotoxin
title_full_unstemmed PAF is a potent pyrogen and cryogen in rodents, but it does not mediate thermoregulatory responses to bacterial endotoxin
title_short PAF is a potent pyrogen and cryogen in rodents, but it does not mediate thermoregulatory responses to bacterial endotoxin
title_sort paf is a potent pyrogen and cryogen in rodents, but it does not mediate thermoregulatory responses to bacterial endotoxin
topic Editorial Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843932/
https://www.ncbi.nlm.nih.gov/pubmed/27227061
http://dx.doi.org/10.1080/23328940.2015.1096439
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