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Reduced oxygen utilization in septic shock: disorder or adaptation?
A fall in oxygen utilization during septic or endotoxic shock is thought to reflect circulatory hypoxia or mitochondrial dysfunction, but these pathology-oriented hypotheses do not explain all clinical observations. Here we discuss an alternative hypothesis of how oxygen utilization could fall as th...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843942/ https://www.ncbi.nlm.nih.gov/pubmed/27227060 http://dx.doi.org/10.1080/23328940.2014.996484 |
| _version_ | 1782428705054785536 |
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| author | Steiner, Alexandre A |
| author_facet | Steiner, Alexandre A |
| author_sort | Steiner, Alexandre A |
| collection | PubMed |
| description | A fall in oxygen utilization during septic or endotoxic shock is thought to reflect circulatory hypoxia or mitochondrial dysfunction, but these pathology-oriented hypotheses do not explain all clinical observations. Here we discuss an alternative hypothesis of how oxygen utilization could fall as the result of a physiological thermometabolic adaptation. |
| format | Online Article Text |
| id | pubmed-4843942 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2015 |
| publisher | Taylor & Francis |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-48439422016-05-25 Reduced oxygen utilization in septic shock: disorder or adaptation? Steiner, Alexandre A Temperature (Austin) Discovery A fall in oxygen utilization during septic or endotoxic shock is thought to reflect circulatory hypoxia or mitochondrial dysfunction, but these pathology-oriented hypotheses do not explain all clinical observations. Here we discuss an alternative hypothesis of how oxygen utilization could fall as the result of a physiological thermometabolic adaptation. Taylor & Francis 2015-02-05 /pmc/articles/PMC4843942/ /pubmed/27227060 http://dx.doi.org/10.1080/23328940.2014.996484 Text en © 2015 The Author(s). Published with license by Taylor & Francis http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted. |
| spellingShingle | Discovery Steiner, Alexandre A Reduced oxygen utilization in septic shock: disorder or adaptation? |
| title | Reduced oxygen utilization in septic shock: disorder or adaptation? |
| title_full | Reduced oxygen utilization in septic shock: disorder or adaptation? |
| title_fullStr | Reduced oxygen utilization in septic shock: disorder or adaptation? |
| title_full_unstemmed | Reduced oxygen utilization in septic shock: disorder or adaptation? |
| title_short | Reduced oxygen utilization in septic shock: disorder or adaptation? |
| title_sort | reduced oxygen utilization in septic shock: disorder or adaptation? |
| topic | Discovery |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843942/ https://www.ncbi.nlm.nih.gov/pubmed/27227060 http://dx.doi.org/10.1080/23328940.2014.996484 |
| work_keys_str_mv | AT steineralexandrea reducedoxygenutilizationinsepticshockdisorderoradaptation |