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Antigen targeting reveals splenic CD169(+) macrophages as promoters of germinal center B‐cell responses
Ag delivery to specific APCs is an attractive approach in developing strategies for vaccination. CD169(+) macrophages in the marginal zone of the spleen represent a suitable target for delivery of Ag because of their strategic location, which is optimal for the capture of blood‐borne Ag and their cl...
Autores principales: | Veninga, Henrike, Borg, Ellen G. F., Vreeman, Kyle, Taylor, Philip R., Kalay, Hakan, van Kooyk, Yvette, Kraal, Georg, Martinez‐Pomares, Luisa, den Haan, Joke M.M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843951/ https://www.ncbi.nlm.nih.gov/pubmed/25487358 http://dx.doi.org/10.1002/eji.201444983 |
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