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Characterisation of the Immunomodulatory Effects of Meningococcal Opa Proteins on Human Peripheral Blood Mononuclear Cells and CD4(+) T Cells

Opa proteins are major surface-expressed proteins located in the Neisseria meningitidis outer membrane, and are potential meningococcal vaccine candidates. Although Opa proteins elicit high levels of bactericidal antibodies following immunisation in mice, progress towards human clinical trials has b...

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Detalles Bibliográficos
Autores principales:	Jones, Claire, Sadarangani, Manish, Lewis, Susan, Payne, Isabelle, Saleem, Muhammad, Derrick, Jeremy P., Pollard, Andrew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844130/ https://www.ncbi.nlm.nih.gov/pubmed/27111850 http://dx.doi.org/10.1371/journal.pone.0154153

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