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Site-specific Proteasome Phosphorylation Controls Cell Proliferation and Tumorigenesis
Despite the fundamental importance of proteasomal degradation in cells, little is known about whether and how the 26S proteasome itself is regulated in coordination with various physiological processes. Here we show that the proteasome is dynamically phosphorylated during cell cycle at Thr25 of the...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844191/ https://www.ncbi.nlm.nih.gov/pubmed/26655835 http://dx.doi.org/10.1038/ncb3289 |