A lincRNA connected to cell mortality and epigenetically-silenced in most common human cancers

Immortality is an essential characteristic of human carcinoma cells. We recently developed an efficient, reproducible method that immortalizes human mammary epithelial cells (HMEC) in the absence of gross genomic changes by targeting 2 critical senescence barriers. Consistent transcriptomic changes...

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Detalles Bibliográficos
Autores principales: Vrba, Lukas, Garbe, James C, Stampfer, Martha R, Futscher, Bernard W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844203/
https://www.ncbi.nlm.nih.gov/pubmed/26646903
http://dx.doi.org/10.1080/15592294.2015.1106673

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844203/
https://www.ncbi.nlm.nih.gov/pubmed/26646903
http://dx.doi.org/10.1080/15592294.2015.1106673

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