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Beyond Telomerase: Telomere Instability as a Novel Target for Cancer Therapy

Telomeres are areas of heterochromatin composed of TTAGGG repeats located at the ends of linear chromosomes. They play a critical role in keeping genome stable and preventing premature aging diseases and the development of cancer. Characterizing mechanisms of telomere maintenance and understanding h...

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Detalles Bibliográficos
Autores principales: Fadri-Moskwik, Maria, Zhou, Qing, Chai, Weihang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844356/
https://www.ncbi.nlm.nih.gov/pubmed/27123041
http://dx.doi.org/10.4172/1747-0862.1000091