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Beyond Telomerase: Telomere Instability as a Novel Target for Cancer Therapy
Telomeres are areas of heterochromatin composed of TTAGGG repeats located at the ends of linear chromosomes. They play a critical role in keeping genome stable and preventing premature aging diseases and the development of cancer. Characterizing mechanisms of telomere maintenance and understanding h...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844356/ https://www.ncbi.nlm.nih.gov/pubmed/27123041 http://dx.doi.org/10.4172/1747-0862.1000091 |