An Experimental Method for Measuring Mechanical Properties of Rat Pulmonary Arteries Verified With Latex

This paper describes a test method for measuring the mechanical properties of small, nonlinear membrane samples from a rat model for pulmonary hypertension. The size and nonlinearity of the pulmonary artery samples poses a challenge for developing a test method that will generate quality, reproducib...

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Detalles Bibliográficos
Autores principales: Drexler, E. S., Slifka, A. J., Wright, J. E., McCowan, C. N., Finch, D. S., Quinn, T. P., McColskey, J. D., Ivy, D. D., Shandas, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: [Gaithersburg, MD] : U.S. Dept. of Commerce, National Institute of Standards and Technology 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844506/
https://www.ncbi.nlm.nih.gov/pubmed/27413604
http://dx.doi.org/10.6028/jres.108.018
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author Drexler, E. S.
Slifka, A. J.
Wright, J. E.
McCowan, C. N.
Finch, D. S.
Quinn, T. P.
McColskey, J. D.
Ivy, D. D.
Shandas, R.
author_facet Drexler, E. S.
Slifka, A. J.
Wright, J. E.
McCowan, C. N.
Finch, D. S.
Quinn, T. P.
McColskey, J. D.
Ivy, D. D.
Shandas, R.
author_sort Drexler, E. S.
collection PubMed
description This paper describes a test method for measuring the mechanical properties of small, nonlinear membrane samples from a rat model for pulmonary hypertension. The size and nonlinearity of the pulmonary artery samples poses a challenge for developing a test method that will generate quality, reproducible data in the pressure range experienced by the hypertensive pulmonary artery. The experimental method described here has sufficient precision to yield a combined relative standard uncertainty of 4 %. The method is calibrated against 75 µm thick latex and the data agree well with the neo-Hookian model.
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spelling pubmed-48445062016-07-13 An Experimental Method for Measuring Mechanical Properties of Rat Pulmonary Arteries Verified With Latex Drexler, E. S. Slifka, A. J. Wright, J. E. McCowan, C. N. Finch, D. S. Quinn, T. P. McColskey, J. D. Ivy, D. D. Shandas, R. J Res Natl Inst Stand Technol Article This paper describes a test method for measuring the mechanical properties of small, nonlinear membrane samples from a rat model for pulmonary hypertension. The size and nonlinearity of the pulmonary artery samples poses a challenge for developing a test method that will generate quality, reproducible data in the pressure range experienced by the hypertensive pulmonary artery. The experimental method described here has sufficient precision to yield a combined relative standard uncertainty of 4 %. The method is calibrated against 75 µm thick latex and the data agree well with the neo-Hookian model. [Gaithersburg, MD] : U.S. Dept. of Commerce, National Institute of Standards and Technology 2003 2003-06-01 /pmc/articles/PMC4844506/ /pubmed/27413604 http://dx.doi.org/10.6028/jres.108.018 Text en https://creativecommons.org/publicdomain/zero/1.0/ The Journal of Research of the National Institute of Standards and Technology is a publication of the U.S. Government. The papers are in the public domain and are not subject to copyright in the United States. Articles from J Res may contain photographs or illustrations copyrighted by other commercial organizations or individuals that may not be used without obtaining prior approval from the holder of the copyright.
spellingShingle Article
Drexler, E. S.
Slifka, A. J.
Wright, J. E.
McCowan, C. N.
Finch, D. S.
Quinn, T. P.
McColskey, J. D.
Ivy, D. D.
Shandas, R.
An Experimental Method for Measuring Mechanical Properties of Rat Pulmonary Arteries Verified With Latex
title An Experimental Method for Measuring Mechanical Properties of Rat Pulmonary Arteries Verified With Latex
title_full An Experimental Method for Measuring Mechanical Properties of Rat Pulmonary Arteries Verified With Latex
title_fullStr An Experimental Method for Measuring Mechanical Properties of Rat Pulmonary Arteries Verified With Latex
title_full_unstemmed An Experimental Method for Measuring Mechanical Properties of Rat Pulmonary Arteries Verified With Latex
title_short An Experimental Method for Measuring Mechanical Properties of Rat Pulmonary Arteries Verified With Latex
title_sort experimental method for measuring mechanical properties of rat pulmonary arteries verified with latex
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844506/
https://www.ncbi.nlm.nih.gov/pubmed/27413604
http://dx.doi.org/10.6028/jres.108.018
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