Fractionated Stereotactic Gamma Knife Radiosurgery for Medial Temporal Lobe Epilepsy: A Case Report

An 18-year-old left-handed male harbored intractable medial temporal lobe epilepsy (MTLE) underwent fractionated gamma knife surgery (GKS) instead of open surgery, considering the mental retardation and diffuse cerebral dysfunction. GKS treatment parameters were: target volume, 8.8 cm(3); total marg...

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Detalles Bibliográficos
Autores principales: Park, Hye Ran, Chung, Hyun-Tai, Lee, Sang Kun, Kim, Dong Gyu, Paek, Sun Ha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Science 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844568/
https://www.ncbi.nlm.nih.gov/pubmed/27122996
http://dx.doi.org/10.5607/en.2016.25.2.93
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author Park, Hye Ran
Chung, Hyun-Tai
Lee, Sang Kun
Kim, Dong Gyu
Paek, Sun Ha
author_facet Park, Hye Ran
Chung, Hyun-Tai
Lee, Sang Kun
Kim, Dong Gyu
Paek, Sun Ha
author_sort Park, Hye Ran
collection PubMed
description An 18-year-old left-handed male harbored intractable medial temporal lobe epilepsy (MTLE) underwent fractionated gamma knife surgery (GKS) instead of open surgery, considering the mental retardation and diffuse cerebral dysfunction. GKS treatment parameters were: target volume, 8.8 cm(3); total marginal dose, 24 Gy in 3 fractionations at the 50% isodose line. The patient has been free from seizures since 9 months after GKS, with notable improvement in cognitive outcome. Fractionated GKS could be considered as a safe tool for seizure control and neuropsychological improvement in patients with MTLE.
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spelling pubmed-48445682016-04-27 Fractionated Stereotactic Gamma Knife Radiosurgery for Medial Temporal Lobe Epilepsy: A Case Report Park, Hye Ran Chung, Hyun-Tai Lee, Sang Kun Kim, Dong Gyu Paek, Sun Ha Exp Neurobiol Case Report An 18-year-old left-handed male harbored intractable medial temporal lobe epilepsy (MTLE) underwent fractionated gamma knife surgery (GKS) instead of open surgery, considering the mental retardation and diffuse cerebral dysfunction. GKS treatment parameters were: target volume, 8.8 cm(3); total marginal dose, 24 Gy in 3 fractionations at the 50% isodose line. The patient has been free from seizures since 9 months after GKS, with notable improvement in cognitive outcome. Fractionated GKS could be considered as a safe tool for seizure control and neuropsychological improvement in patients with MTLE. The Korean Society for Brain and Neural Science 2016-04 2016-03-31 /pmc/articles/PMC4844568/ /pubmed/27122996 http://dx.doi.org/10.5607/en.2016.25.2.93 Text en Copyright © Experimental Neurobiology 2016. http://creativecommons.org/licenses/by-nc/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Park, Hye Ran
Chung, Hyun-Tai
Lee, Sang Kun
Kim, Dong Gyu
Paek, Sun Ha
Fractionated Stereotactic Gamma Knife Radiosurgery for Medial Temporal Lobe Epilepsy: A Case Report
title Fractionated Stereotactic Gamma Knife Radiosurgery for Medial Temporal Lobe Epilepsy: A Case Report
title_full Fractionated Stereotactic Gamma Knife Radiosurgery for Medial Temporal Lobe Epilepsy: A Case Report
title_fullStr Fractionated Stereotactic Gamma Knife Radiosurgery for Medial Temporal Lobe Epilepsy: A Case Report
title_full_unstemmed Fractionated Stereotactic Gamma Knife Radiosurgery for Medial Temporal Lobe Epilepsy: A Case Report
title_short Fractionated Stereotactic Gamma Knife Radiosurgery for Medial Temporal Lobe Epilepsy: A Case Report
title_sort fractionated stereotactic gamma knife radiosurgery for medial temporal lobe epilepsy: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844568/
https://www.ncbi.nlm.nih.gov/pubmed/27122996
http://dx.doi.org/10.5607/en.2016.25.2.93
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