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Surgery-Induced Hippocampal Angiotensin II Elevation Causes Blood-Brain Barrier Disruption via MMP/TIMP in Aged Rats

Reversible blood-brain barrier (BBB) disruption has been uniformly reported in several animal models of postoperative cognitive dysfunction (POCD). Nevertheless, the precise mechanism underlying this occurrence remains unclear. Using an aged rat model of POCD, we investigated the dynamic changes in...

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Detalles Bibliográficos
Autores principales:	Li, Zhengqian, Mo, Na, Li, Lunxu, Cao, Yiyun, Wang, Wenming, Liang, Yaoxian, Deng, Hui, Xing, Rui, Yang, Lin, Ni, Cheng, Chui, Dehua, Guo, Xiangyang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844612/ https://www.ncbi.nlm.nih.gov/pubmed/27199659 http://dx.doi.org/10.3389/fncel.2016.00105

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