The molecular basis of the genesis of basal tone in internal anal sphincter

Smooth muscle sphincters exhibit basal tone and control passage of contents through organs such as the gastrointestinal tract; loss of this tone leads to disorders such as faecal incontinence. However, the molecular mechanisms underlying this tone remain unknown. Here, we show that deletion of myosi...

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Detalles Bibliográficos
Autores principales: Zhang, Cheng-Hai, Wang, Pei, Liu, Dong-Hai, Chen, Cai-Ping, Zhao, Wei, Chen, Xin, Chen, Chen, He, Wei-Qi, Qiao, Yan-Ning, Tao, Tao, Sun, Jie, Peng, Ya-Jing, Lu, Ping, Zheng, Kaizhi, Craige, Siobhan M., Lifshitz, Lawrence M., Keaney Jr, John F., Fogarty, Kevin E., ZhuGe, Ronghua, Zhu, Min-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844698/
https://www.ncbi.nlm.nih.gov/pubmed/27101932
http://dx.doi.org/10.1038/ncomms11358

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