Design of a RANK-Mimetic Peptide Inhibitor of Osteoclastogenesis with Enhanced RANKL-Binding Affinity

The receptor activator of nuclear factor κB (RANK) and its ligand RANKL are key regulators of osteoclastogenesis and well-recognized targets in developing treatments for bone disorders associated with excessive bone resorption, such as osteoporosis. Our previous work on the structure of the RANK-RAN...

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Detalles Bibliográficos
Autores principales: Hur, Jeonghwan, Ghosh, Ambarnil, Kim, Kabsun, Ta, Hai Minh, Kim, Hyunju, Kim, Nacksung, Hwang, Hye-Yeon, Kim, Kyeong Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844938/
https://www.ncbi.nlm.nih.gov/pubmed/26923188
http://dx.doi.org/10.14348/molcells.2016.2286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844938/
https://www.ncbi.nlm.nih.gov/pubmed/26923188
http://dx.doi.org/10.14348/molcells.2016.2286

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