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Efficient Generation of Myostatin Gene Mutated Rabbit by CRISPR/Cas9

CRISPR/Cas9 has been widely used in generating site-specific genetically modified animal models. Myostatin (MSTN) is a negative regulator of muscle mass, related to muscle growth and differentiation. The knockout of MSTN with the desired phenotype of double muscle has been successfully generated in...

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Detalles Bibliográficos
Autores principales:	Lv, Qingyan, Yuan, Lin, Deng, Jichao, Chen, Mao, Wang, Yong, Zeng, Jian, Li, Zhanjun, Lai, Liangxue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844959/ https://www.ncbi.nlm.nih.gov/pubmed/27113799 http://dx.doi.org/10.1038/srep25029

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