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Smad6 determines BMP-regulated invasive behaviour of breast cancer cells in a zebrafish xenograft model
The transforming growth factor-β (TGF-β) family is known to play critical roles in cancer progression. While the dual role of TGF-β is well described, the function of bone morphogenetic proteins (BMPs) is unclear. In this study, we established the involvement of Smad6, a BMP-specific inhibitory Smad...
Autores principales: | de Boeck, Miriam, Cui, Chao, Mulder, Aat A, Jost, Carolina R, Ikeno, Souichi, ten Dijke, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844967/ https://www.ncbi.nlm.nih.gov/pubmed/27113436 http://dx.doi.org/10.1038/srep24968 |
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