Human somatic cells subjected to genetic induction with six germ line-related factors display meiotic germ cell-like features

The in vitro derivation of human germ cells has attracted interest in the last years, but their direct conversion from human somatic cells has not yet been reported. Here we tested the ability of human male somatic cells to directly convert into a meiotic germ cell-like phenotype by inducing them wi...

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Detalles Bibliográficos
Autores principales: Medrano, Jose V., Martínez-Arroyo, Ana M., Míguez, Jose M., Moreno, Inmaculada, Martínez, Sebastián, Quiñonero, Alicia, Díaz-Gimeno, Patricia, Marqués-Marí, Ana I., Pellicer, Antonio, Remohí, Jose, Simón, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844986/
https://www.ncbi.nlm.nih.gov/pubmed/27112843
http://dx.doi.org/10.1038/srep24956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844986/
https://www.ncbi.nlm.nih.gov/pubmed/27112843
http://dx.doi.org/10.1038/srep24956

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