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Human somatic cells subjected to genetic induction with six germ line-related factors display meiotic germ cell-like features
The in vitro derivation of human germ cells has attracted interest in the last years, but their direct conversion from human somatic cells has not yet been reported. Here we tested the ability of human male somatic cells to directly convert into a meiotic germ cell-like phenotype by inducing them wi...
Autores principales: | Medrano, Jose V., Martínez-Arroyo, Ana M., Míguez, Jose M., Moreno, Inmaculada, Martínez, Sebastián, Quiñonero, Alicia, Díaz-Gimeno, Patricia, Marqués-Marí, Ana I., Pellicer, Antonio, Remohí, Jose, Simón, Carlos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844986/ https://www.ncbi.nlm.nih.gov/pubmed/27112843 http://dx.doi.org/10.1038/srep24956 |
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