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Proteomic dissection of LPS-inducible, PHF8-dependent secretome reveals novel roles of PHF8 in TLR4-induced acute inflammation and T cell proliferation

Endotoxin (LPS)-induced changes in histone lysine methylation contribute to the gene-specific transcription for control of inflammation. Still unidentified are the chromatin regulators that drive the transition from a transcriptional-repressive to a transcriptional-active chromatin state of pro-infl...

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Detalles Bibliográficos
Autores principales: Erdoğan, Özgün, Xie, Ling, Wang, Li, Wu, Bing, Kong, Qing, Wan, Yisong, Chen, Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845005/
https://www.ncbi.nlm.nih.gov/pubmed/27112199
http://dx.doi.org/10.1038/srep24833

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