Preparation data of the bromodomains BRD3(1), BRD3(2), BRD4(1), and BRPF1B and crystallization of BRD4(1)-inhibitor complexes

This article presents detailed purification procedures for the bromodomains BRD3(1), BRD3(2), BRD4(1), and BRPF1B. In addition we provide crystallization protocols for apo BRD4(1) and BRD4(1) in complex with numerous inhibitors. The protocols described here were successfully applied to obtain affini...

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Detalles Bibliográficos
Autores principales: Hügle, Martin, Lucas, Xavier, Weitzel, Gerhard, Ostrovskyi, Dmytro, Breit, Bernhard, Gerhardt, Stefan, Schmidtkunz, Karin, Jung, Manfred, Schüle, Roland, Einsle, Oliver, Günther, Stefan, Wohlwend, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Data Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845076/
https://www.ncbi.nlm.nih.gov/pubmed/27158652
http://dx.doi.org/10.1016/j.dib.2016.04.009

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