Cargando…

Oxylipid Profile of Low‐Dose Aspirin Exposure: A Pharmacometabolomics Study

BACKGROUND: While aspirin is a well‐established and generally effective anti‐platelet agent, considerable inter‐individual variation in drug response exists, for which mechanisms are not completely understood. Metabolomics allows for extensive measurement of small molecules in biological samples, en...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ellero‐Simatos, Sandrine, Beitelshees, Amber L., Lewis, Joshua P., Yerges‐Armstrong, Laura M., Georgiades, Anastasia, Dane, Adrie, Harms, Amy C., Strassburg, Katrin, Guled, Faisa, Hendriks, Margriet M. W. B., Horenstein, Richard B., Shuldiner, Alan R., Hankemeier, Thomas, Kaddurah‐Daouk, Rima
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845113/ https://www.ncbi.nlm.nih.gov/pubmed/26504148 http://dx.doi.org/10.1161/JAHA.115.002203

Ejemplares similares

Purine Pathway Implicated in Mechanism of Resistance to Aspirin Therapy: Pharmacometabolomics-Informed-Pharmacogenomics
por: Yerges-Armstrong, Laura M., et al.
Publicado: (2013)

Pharmacometabolomics Reveals That Serotonin Is Implicated in Aspirin Response Variability
por: Ellero-Simatos, S, et al.
Publicado: (2014)

Current Concepts in Pharmacometabolomics, Biomarker Discovery, and Precision Medicine
por: Beger, Richard D., et al.
Publicado: (2020)

Pharmacometabolomics Informs About Pharmacokinetic Profile of Methylphenidate
por: Kaddurah‐Daouk, Rima, et al.
Publicado: (2018)

Pharmacometabolomics Reveals Racial Differences in Response to Atenolol Treatment
por: Wikoff, William R., et al.
Publicado: (2013)

Pharmacometabolomic Assessment of Metformin in Non-diabetic, African Americans
por: Rotroff, Daniel M., et al.
Publicado: (2016)

Pharmacometabolomic Assessments of Atenolol and Hydrochlorothiazide Treatment Reveal Novel Drug Response Phenotypes
por: Rotroff, DM, et al.
Publicado: (2015)

Pharmacometabolomic Signature of Ataxia SCA1 Mouse Model and Lithium Effects
por: Perroud, Bertrand, et al.
Publicado: (2013)

Systematic Evaluation of HILIC Stationary Phases for Global Metabolomics of Human Plasma
por: Hosseinkhani, Farideh, et al.
Publicado: (2022)

Pharmacometabolomic mapping of early biochemical changes induced by sertraline and placebo
por: Kaddurah-Daouk, R, et al.
Publicado: (2013)

Pharmacometabolomics of Response to Sertraline and to Placebo in Major Depressive Disorder – Possible Role for Methoxyindole Pathway
por: Zhu, Hongjie, et al.
Publicado: (2013)

Periparturient lipolysis and oxylipid biosynthesis in bovine adipose tissues
por: Contreras, G. Andres, et al.
Publicado: (2017)

Integration of pharmacometabolomics with pharmacokinetics and pharmacodynamics: towards personalized drug therapy
por: Kantae, Vasudev, et al.
Publicado: (2016)

Metabolic Profiling of Patients with Schizophrenia
por: Kaddurah-Daouk, Rima
Publicado: (2006)

TSPAN5, ERICH3 and selective serotonin reuptake inhibitors in major depressive disorder: pharmacometabolomics-informed pharmacogenomics
por: Gupta, M, et al.
Publicado: (2016)

Influence of Sex on Platelet Reactivity in Response to Aspirin
por: Friede, Kevin A., et al.
Publicado: (2020)

Distinct Signature of Oxylipid Mediators of Inflammation during Infection and Asymptomatic Colonization by E. coli in the Urinary Bladder
por: Packiriswamy, Nandakumar, et al.
Publicado: (2017)

Postpartum meloxicam administration alters plasma haptoglobin, polyunsaturated fatty acid, and oxylipid concentrations in postpartum ewes
por: Olagaray, Katie E., et al.
Publicado: (2020)

Prediction of Low-Dose Aspirin-Induced Gastric Toxicity Using Nuclear Magnetic Resonance Spectroscopy-Based Pharmacometabolomics in Rats
por: Sha’aban, Abubakar, et al.
Publicado: (2022)

Pharmacometabolomics-aided Pharmacogenomics in Autoimmune Disease
por: Katsila, Theodora, et al.
Publicado: (2016)

Pharmacometabolomics in Early‐Phase Clinical Development
por: Burt, T, et al.
Publicado: (2016)

Pharmacokinetics in Pharmacometabolomics: Towards Personalized Medication
por: Jian, Jingai, et al.
Publicado: (2023)

Pharmacometabolomics Informs Viromics toward Precision Medicine
por: Balasopoulou, Angeliki, et al.
Publicado: (2016)

Pharmacometabolomics of Meglumine Antimoniate in Patients With Cutaneous Leishmaniasis
por: Vargas, Deninson Alejandro, et al.
Publicado: (2019)

Pharmacometabolomics by NMR in Oncology: A Systematic Review
por: Gómez-Cebrián, Nuria, et al.
Publicado: (2021)

Pharmacometabolomics Applied to Personalized Medicine in Urological Cancers
por: Amaro, Filipa, et al.
Publicado: (2022)

Distinct profiles of oxylipid mediators in liver, lung, and placenta after maternal nano-TiO(2) nanoparticle inhalation exposure
por: Harris, Todd R., et al.
Publicado: (2023)

Pharmacometabolomic Approach to Predict QT Prolongation in Guinea Pigs
por: Park, Jeonghyeon, et al.
Publicado: (2013)

Pharmacometabolomics for the Study of Lipid-Lowering Therapies: Opportunities and Challenges
por: Gianazza, Erica, et al.
Publicado: (2023)

Pharmacometabolomics of trabectedin in metastatic soft tissue sarcoma patients
por: Corona, Giuseppe, et al.
Publicado: (2023)

The Personalization of Clopidogrel Antiplatelet Therapy: The Role of Integrative Pharmacogenetics and Pharmacometabolomics
por: Amin, Arwa M., et al.
Publicado: (2017)

Pharmacometabolomics of Bronchodilator Response in Asthma and the Role of Age-Metabolite Interactions
por: Kelly, Rachel S., et al.
Publicado: (2019)

The gut microbiota: a major player in the toxicity of environmental pollutants?
por: Claus, Sandrine P, et al.
Publicado: (2017)

The gut microbiota: a major player in the toxicity of environmental pollutants?
por: Claus, Sandrine P, et al.
Publicado: (2016)

Prospective Evaluation of Genetic Variation in Platelet Endothelial Aggregation Receptor 1 Reveals Aspirin‐Dependent Effects on Platelet Aggregation Pathways
por: Backman, JD, et al.
Publicado: (2017)

Pharmacometabolomic profiles in type 2 diabetic subjects treated with liraglutide or glimepiride
por: Jendle, J., et al.
Publicado: (2021)

Pharmacometabolomics of Respiratory Phenotypic Response to Dexamethasone in Preterm Infants at Risk for Bronchopulmonary Dysplasia
por: Lewis, Tamorah, et al.
Publicado: (2019)

Assessing the metabolic effects of prednisolone in healthy volunteers using urine metabolic profiling
por: Ellero-Simatos, Sandrine, et al.
Publicado: (2012)

Module-Based Association Analysis for Omics Data with Network Structure
por: Wang, Zhi, et al.
Publicado: (2015)

Pharmacometabolomic prediction of individual differences of gastrointestinal toxicity complicating myelosuppression in rats induced by irinotecan
por: Gao, Yiqiao, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_4bb13tq015nbfjob5r2kqr17ks