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Development of Aortic Valve Disease in Familial Hypercholesterolemic Swine: Implications for Elucidating Disease Etiology

BACKGROUND: Familial hypercholesterolemia (FH) is a prevalent hereditary disease associated with increased atherosclerosis and calcific aortic valve disease (CAVD). However, in both FH and non‐FH individuals, the role of hypercholesterolemia in the development of CAVD is poorly understood. This stud...

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Detalles Bibliográficos
Autores principales: Porras, Ana M., Shanmuganayagam, Dhanansayan, Meudt, Jennifer J., Krueger, Christian G., Hacker, Timothy A., Rahko, Peter S., Reed, Jess D., Masters, Kristyn S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845146/
https://www.ncbi.nlm.nih.gov/pubmed/26508741
http://dx.doi.org/10.1161/JAHA.115.002254