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An expanded role for mTORC1 in autophagy

Mechanistic target of rapamycin complex 1 (mTORC1) negatively regulates autophagy at early stages by phosphorylating Unc51-like kinase 1 (ULK1). Our recent study expanded the roles of mTORC1 in autophagy by identifying ultraviolet radiation resistance-associated gene product (UVRAG) as a substrate o...

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Detalles Bibliográficos
Autores principales:	Kim, Young-Mi, Park, Ji-Man, Grunwald, Douglas, Kim, Do-Hyung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2015
Materias:	Author's View
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845164/ https://www.ncbi.nlm.nih.gov/pubmed/27308528 http://dx.doi.org/10.1080/23723556.2015.1010958

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