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DNA damage tolerance branches out toward sister chromatid cohesion
Genome duplication is temporarily coordinated with sister chromatid cohesion and DNA damage tolerance. Recently, we found that replication fork-coupled repriming is important for both optimal cohesion and error-free replication by recombination. The mechanism involved has implications for the etiolo...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845193/ https://www.ncbi.nlm.nih.gov/pubmed/27308553 http://dx.doi.org/10.1080/23723556.2015.1035478 |
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author | Branzei, Dana |
author_facet | Branzei, Dana |
author_sort | Branzei, Dana |
collection | PubMed |
description | Genome duplication is temporarily coordinated with sister chromatid cohesion and DNA damage tolerance. Recently, we found that replication fork-coupled repriming is important for both optimal cohesion and error-free replication by recombination. The mechanism involved has implications for the etiology of replication-based genetic diseases and cancer. |
format | Online Article Text |
id | pubmed-4845193 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Taylor & Francis |
record_format | MEDLINE/PubMed |
spelling | pubmed-48451932016-06-15 DNA damage tolerance branches out toward sister chromatid cohesion Branzei, Dana Mol Cell Oncol Author's View Genome duplication is temporarily coordinated with sister chromatid cohesion and DNA damage tolerance. Recently, we found that replication fork-coupled repriming is important for both optimal cohesion and error-free replication by recombination. The mechanism involved has implications for the etiology of replication-based genetic diseases and cancer. Taylor & Francis 2015-05-07 /pmc/articles/PMC4845193/ /pubmed/27308553 http://dx.doi.org/10.1080/23723556.2015.1035478 Text en © 2016 The Author(s). Published with license by Taylor & Francis http://creativecommons.org/licenses/by/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted. |
spellingShingle | Author's View Branzei, Dana DNA damage tolerance branches out toward sister chromatid cohesion |
title | DNA damage tolerance branches out toward sister chromatid cohesion |
title_full | DNA damage tolerance branches out toward sister chromatid cohesion |
title_fullStr | DNA damage tolerance branches out toward sister chromatid cohesion |
title_full_unstemmed | DNA damage tolerance branches out toward sister chromatid cohesion |
title_short | DNA damage tolerance branches out toward sister chromatid cohesion |
title_sort | dna damage tolerance branches out toward sister chromatid cohesion |
topic | Author's View |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845193/ https://www.ncbi.nlm.nih.gov/pubmed/27308553 http://dx.doi.org/10.1080/23723556.2015.1035478 |
work_keys_str_mv | AT branzeidana dnadamagetolerancebranchesouttowardsisterchromatidcohesion |