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The stress of coping with E2F loss

E2F transcription factors are key regulators of cellular proliferation, and altered E2F activity is a common feature of tumor cells. Thus, E2F targeting is being explored as a therapeutic strategy in cancer. Importantly, recent mouse knockout studies show that concomitant loss of E2f1/E2f2 activity...

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Detalles Bibliográficos
Autores principales: Iglesias-Ara, Ainhoa, Zubiaga, Ana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845195/
https://www.ncbi.nlm.nih.gov/pubmed/27308555
http://dx.doi.org/10.1080/23723556.2015.1038423