Metabolic rewiring in cancer-associated fibroblasts provides a niche for oncogenesis and metastatic dissemination

Cancer-associated fibroblasts (CAFs) are major participants in the crosstalk between tumor cells and their microenvironment. CAFs provide not only multiple soluble factors but also metabolic fuels to promote tumor growth, invasion, and metastasis. We discuss recent developments delineating the effec...

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Detalles Bibliográficos
Autores principales: Liu, Jingyi, Mi, Jun, Zhou, Binhua P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Author's View - Commissioned
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845206/
https://www.ncbi.nlm.nih.gov/pubmed/27308568
http://dx.doi.org/10.1080/23723556.2015.1056331
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author Liu, Jingyi
Mi, Jun
Zhou, Binhua P.
author_facet Liu, Jingyi
Mi, Jun
Zhou, Binhua P.
author_sort Liu, Jingyi
collection PubMed
description Cancer-associated fibroblasts (CAFs) are major participants in the crosstalk between tumor cells and their microenvironment. CAFs provide not only multiple soluble factors but also metabolic fuels to promote tumor growth, invasion, and metastasis. We discuss recent developments delineating the effects of metabolic symbiosis between CAFs and tumor cells on tumor growth.
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spelling pubmed-48452062016-12-14 Metabolic rewiring in cancer-associated fibroblasts provides a niche for oncogenesis and metastatic dissemination Liu, Jingyi Mi, Jun Zhou, Binhua P. Mol Cell Oncol Author's View - Commissioned Cancer-associated fibroblasts (CAFs) are major participants in the crosstalk between tumor cells and their microenvironment. CAFs provide not only multiple soluble factors but also metabolic fuels to promote tumor growth, invasion, and metastasis. We discuss recent developments delineating the effects of metabolic symbiosis between CAFs and tumor cells on tumor growth. Taylor & Francis 2015-12-14 /pmc/articles/PMC4845206/ /pubmed/27308568 http://dx.doi.org/10.1080/23723556.2015.1056331 Text en © 2016 The Author(s). Published with license by Taylor & Francis Group, LLC http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
spellingShingle Author's View - Commissioned
Liu, Jingyi
Mi, Jun
Zhou, Binhua P.
Metabolic rewiring in cancer-associated fibroblasts provides a niche for oncogenesis and metastatic dissemination
title Metabolic rewiring in cancer-associated fibroblasts provides a niche for oncogenesis and metastatic dissemination
title_full Metabolic rewiring in cancer-associated fibroblasts provides a niche for oncogenesis and metastatic dissemination
title_fullStr Metabolic rewiring in cancer-associated fibroblasts provides a niche for oncogenesis and metastatic dissemination
title_full_unstemmed Metabolic rewiring in cancer-associated fibroblasts provides a niche for oncogenesis and metastatic dissemination
title_short Metabolic rewiring in cancer-associated fibroblasts provides a niche for oncogenesis and metastatic dissemination
title_sort metabolic rewiring in cancer-associated fibroblasts provides a niche for oncogenesis and metastatic dissemination
topic Author's View - Commissioned
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845206/
https://www.ncbi.nlm.nih.gov/pubmed/27308568
http://dx.doi.org/10.1080/23723556.2015.1056331
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AT mijun metabolicrewiringincancerassociatedfibroblastsprovidesanicheforoncogenesisandmetastaticdissemination
AT zhoubinhuap metabolicrewiringincancerassociatedfibroblastsprovidesanicheforoncogenesisandmetastaticdissemination

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