Tumor Necrosis Factor–Related Apoptosis‐Inducing Ligand (TRAIL) Promotes Angiogenesis and Ischemia‐Induced Neovascularization Via NADPH Oxidase 4 (NOX4) and Nitric Oxide–Dependent Mechanisms

BACKGROUND: Tumor necrosis factor–related apoptosis‐inducing ligand (TRAIL) has the ability to inhibit angiogenesis by inducing endothelial cell death, as well as being able to promote pro‐angiogenic activity in vitro. These seemingly opposite effects make its role in ischemic disease unclear. Using...

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Detalles Bibliográficos
Autores principales: Di Bartolo, Belinda Ann, Cartland, Siân Peta, Prado‐Lourenco, Leonel, Griffith, Thomas Scott, Gentile, Carmine, Ravindran, Jayant, Azahri, Nor Saadah Muhammad, Thai, Thuan, Yeung, Amanda Wing Shee, Thomas, Shane Ross, Kavurma, Mary Meltem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845240/
https://www.ncbi.nlm.nih.gov/pubmed/26572549
http://dx.doi.org/10.1161/JAHA.115.002527

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