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Reassessing the role of NAD as a prosurvival factor
The mechanisms regulating the choice of cell demise remain largely unknown. NAD(+), a key metabolite with well-known roles in cell metabolism, has been shown to counteract apoptosis while promoting necroptosis, a form of proinflammatory cell death. This observation identifies NAD(+) availability as...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845243/ https://www.ncbi.nlm.nih.gov/pubmed/27308572 http://dx.doi.org/10.1080/23723556.2015.1062591 |