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Chloroquine anticancer activity is mediated by autophagy-independent effects on the tumor vasculature
Chloroquine is used clinically as an autophagy blocker to potentiate anticancer treatments. However, whether chloroquine acts solely through autophagy-dependent and cancer cell autonomous mechanisms has remained elusive. In a recent study we found that chloroquine reduced intratumoral hypoxia and me...
Autores principales: | Maes, Hannelore, Kuchnio, Anna, Carmeliet, Peter, Agostinis, Patrizia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845249/ https://www.ncbi.nlm.nih.gov/pubmed/27308577 http://dx.doi.org/10.4161/23723548.2014.970097 |
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