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Network-driven plasma proteomics expose molecular changes in the Alzheimer’s brain
BACKGROUND: Biological pathways that significantly contribute to sporadic Alzheimer’s disease are largely unknown and cannot be observed directly. Cognitive symptoms appear only decades after the molecular disease onset, further complicating analyses. As a consequence, molecular research is often re...
Autores principales: | Jaeger, Philipp A., Lucin, Kurt M., Britschgi, Markus, Vardarajan, Badri, Huang, Ruo-Pan, Kirby, Elizabeth D., Abbey, Rachelle, Boeve, Bradley F., Boxer, Adam L., Farrer, Lindsay A., Finch, NiCole, Graff-Radford, Neill R., Head, Elizabeth, Hoffree, Matan, Huang, Ruochun, Johns, Hudson, Karydas, Anna, Knopman, David S., Loboda, Andrey, Masliah, Eliezer, Narasimhan, Ramya, Petersen, Ronald C., Podtelezhnikov, Alexei, Pradhan, Suraj, Rademakers, Rosa, Sun, Chung-Huan, Younkin, Steven G., Miller, Bruce L., Ideker, Trey, Wyss-Coray, Tony |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845325/ https://www.ncbi.nlm.nih.gov/pubmed/27112350 http://dx.doi.org/10.1186/s13024-016-0095-2 |
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