The trans-well coculture of human synovial mesenchymal stem cells with chondrocytes leads to self-organization, chondrogenic differentiation, and secretion of TGFβ

BACKGROUND: Synovial mesenchymal stem cells (SMSC) possess a high chondrogenic differentiation potential, which possibly supports natural and surgically induced healing of cartilage lesions. We hypothesized enhanced chondrogenesis of SMSC caused by the vicinity of chondrocytes (CHDR). METHODS: Human...

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Detalles Bibliográficos
Autores principales: Kubosch, Eva Johanna, Heidt, Emanuel, Bernstein, Anke, Böttiger, Katharina, Schmal, Hagen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845486/
https://www.ncbi.nlm.nih.gov/pubmed/27118471
http://dx.doi.org/10.1186/s13287-016-0322-3

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