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In vivo Wnt pathway inhibition of human squamous cell carcinoma growth and metastasis in the chick chorioallantoic model

BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) is an aggressive cancer with poor overall survival. New therapeutic strategies that target specific molecular lesions driving advanced disease are needed. Herein we demonstrate the utility of the chicken chorioallantoic membrane (CAM) assay f...

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Detalles Bibliográficos
Autores principales: Rudy, Shannon F., Brenner, J. Chad, Harris, Jennifer L., Liu, Jun, Che, Jianwei, Scott, Megan V., Owen, John Henry, Komarck, Christine M., P. Graham, Martin, L. Bellile, Emily, Bradford, Carol R., Prince, Mark EP, Carey, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845503/
https://www.ncbi.nlm.nih.gov/pubmed/27117272
http://dx.doi.org/10.1186/s40463-016-0140-8