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A seeding based cellular assay of tauopathy

BACKGROUND: Tauopathy is characterized by neurofibrillary tangles composed of insoluble hyperphosphorylated tau protein. Currently, cellular models that mimic neurofibrillary tangles in vitro are lacking. Previous studies indicate that neurofibrillary tangles form via a prion replication mechanism....

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Detalles Bibliográficos
Autores principales:	Xu, Yin, Martini-Stoica, Heidi, Zheng, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845507/ https://www.ncbi.nlm.nih.gov/pubmed/27112488 http://dx.doi.org/10.1186/s13024-016-0100-9

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