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The Effects of Cetirizine on P-glycoprotein Expression and Function In vitro and In situ

Purpose: P-glycoprotein (P-gp) plays a major role in oral absorption of drugs. Induction or inhibition of P-gp by drugs contributes to variability of its transport activity and often results in clinically relevant drug-drug interactions. The purpose of this study was to investigate the effect of cet...

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Detalles Bibliográficos
Autores principales: Mesgari Abbasi, Mehran, Valizadeh, Hadi, Hamishekar, Hamed, Mohammadnejad, Leila, Zakeri-Milani, Parvin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845543/
https://www.ncbi.nlm.nih.gov/pubmed/27123426
http://dx.doi.org/10.15171/apb.2016.017