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Comparative Study of Different Combinational Mucoadhesive Formulations of Sumatriptan-Metoclopramide
Purpose: Sumatriptan succinate (Sum) is a Serotonin 5- HT1 receptor agonist, used in the treatment of migraine. It is absorbed rapidly but incompletely when taken orally and underwent first - pass metabolism, resulting in a low bioavailability of about 15%. The aim was to design mucoadhesive buccal...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Tabriz University of Medical Sciences
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845549/ https://www.ncbi.nlm.nih.gov/pubmed/27123427 http://dx.doi.org/10.15171/apb.2016.018 |