Improved tag-switch method reveals that thioredoxin acts as depersulfidase and controls the intracellular levels of protein persulfidation

Hydrogen sulfide (H(2)S) has emerged as a signalling molecule capable of regulating several important physiological functions such as blood pressure, neurotransmission and inflammation. The mechanisms behind these effects are still largely elusive and oxidative posttranslational modification of cyst...

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Detalles Bibliográficos
Autores principales: Wedmann, Rudolf, Onderka, Constantin, Wei, Shengwei, Szijártó, István András, Miljkovic, Jan Lj., Mitrovic, Aleksandra, Lange, Mike, Savitsky, Sergey, Yadav, Pramod Kumar, Torregrossa, Roberta, Harrer, Ellen G., Harrer, Thomas, Ishii, Isao, Gollasch, Maik, Wood, Mark E., Galardon, Erwan, Xian, Ming, Whiteman, Matthew, Banerjee, Ruma, Filipovic, Milos R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845716/
https://www.ncbi.nlm.nih.gov/pubmed/27170841
http://dx.doi.org/10.1039/c5sc04818d

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