Integrated multiomics approach identifies calcium and integrin-binding protein-2 as a novel gene for pulse wave velocity

BACKGROUND: Carotid-femoral pulse wave velocity (PWV) is an important measure of arterial stiffness, which is an independent predictor of cardiovascular morbidity and mortality. In this study, we used an integrated genetic, epigenetic and transcriptomics approach to uncover novel molecular mechanism...

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Detalles Bibliográficos
Autores principales: Mangino, Massimo, Cecelja, Marina, Menni, Cristina, Tsai, Pei-Chien, Yuan, Wei, Small, Kerrin, Bell, Jordana, Mitchell, Gary F., Chowienczyk, Phillip, Spector, Tim D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
ORIGINAL PAPERS: Genetic aspects
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845763/
https://www.ncbi.nlm.nih.gov/pubmed/26378684
http://dx.doi.org/10.1097/HJH.0000000000000732

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