Cargando…

Prevention of COPD exacerbation by lysozyme: a double-blind, randomized, placebo-controlled study

BACKGROUND/AIM: Lysozyme (mucopeptide N-acetyl-muramyl hydrolase) is widely used as a mucolytic and anti-inflammatory agent in Japan. We evaluated the effects of long-term lysozyme administration on COPD exacerbation. METHODS: In a 1-year, randomized, double-blind, placebo-controlled, parallel trial...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fukuchi, Yoshinosuke, Tatsumi, Koichiro, Inoue, Hiromasa, Sakata, Yukinori, Shibata, Kai, Miyagishi, Hideaki, Marukawa, Yasuhiro, Ichinose, Masakazu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846053/ https://www.ncbi.nlm.nih.gov/pubmed/27143873 http://dx.doi.org/10.2147/COPD.S103105

Ejemplares similares

COPD uncovered: a cross-sectional study to assess the socioeconomic burden of COPD in Japan
por: Igarashi, Ataru, et al.
Publicado: (2018)

Efficacy and safety of inhaled formoterol 4.5 and 9 μg twice daily in Japanese and European COPD patients: Phase III study results
por: Bogdan, Miron A, et al.
Publicado: (2011)

The efficacy and safety of combined tiotropium and olodaterol via the Respimat(®) inhaler in patients with COPD: results from the Japanese sub-population of the Tonado(®) studies
por: Ichinose, Masakazu, et al.
Publicado: (2016)

Prevalence and characteristics of asthma–COPD overlap syndrome identified by a stepwise approach
por: Inoue, Hiromasa, et al.
Publicado: (2017)

Efficacy and safety of the long-acting β(2)-agonist olodaterol over 4 weeks in Japanese patients with chronic obstructive pulmonary disease
por: Ichinose, Masakazu, et al.
Publicado: (2015)

Imidafenacin, An Orally Active Muscarinic Receptor Antagonist, Improves Pulmonary Function In Patients With Chronic Obstructive Pulmonary Disease: A Multicenter, Randomized, Double-Blind, Placebo-Controlled 3×3 Crossover Phase II Trial
por: Machida, Kentaro, et al.
Publicado: (2019)

Concomitant therapy with Cineole (Eucalyptole) reduces exacerbations in COPD: A placebo-controlled double-blind trial
por: Worth, Heinrich, et al.
Publicado: (2009)

The effect of vitamin D on COPD exacerbation: a double blind randomized placebo-controlled parallel clinical trial
por: Sanjari, Mojgan, et al.
Publicado: (2016)

Randomized double blind placebo-controlled study to demonstrate that antibiotics are not needed in moderate acute exacerbations of COPD – The ABACOPD Study
por: Rohde, Gernot G U, et al.
Publicado: (2015)

A Randomized Double-Blind Placebo-Control Feasibility Trial of Immunoglobulin Treatment for Prevention of Recurrent Acute Exacerbations of COPD
por: Cowan, Juthaporn, et al.
Publicado: (2021)

Nemiralisib in Patients with an Acute Exacerbation of COPD: Placebo-Controlled, Dose-Ranging Study
por: Fahy, William A, et al.
Publicado: (2021)

Exacerbations of COPD
por: Pavord, Ian D, et al.
Publicado: (2016)

Exacerbations of COPD
por: Viniol, Christian, et al.
Publicado: (2018)

Indacaterol/glycopyrronium versus salmeterol/fluticasone in Asian patients with COPD at a high risk of exacerbations: results from the FLAME study
por: Wedzicha, Jadwiga A, et al.
Publicado: (2017)

The Cholinergic Pathways in Inflammation: A Potential Pharmacotherapeutic Target for COPD
por: Yamada, Mitsuhiro, et al.
Publicado: (2018)

Prognostic Nutritional Index (PNI) as a Potential Prognostic Tool for Exacerbation of COPD in Elderly Patients
por: Suzuki, Eiko, et al.
Publicado: (2023)

Consolidation and Exacerbation of COPD
por: Hurst, John R.
Publicado: (2018)

Acute Exacerbation of COPD
por: Lief, Lindsay, et al.
Publicado: (2019)

Management of exacerbations of COPD
por: Seemungal, Terence, et al.
Publicado: (2003)

Acute Exacerbations of COPD
por: Wedzicha, J.A.
Publicado: (2002)

Acute Exacerbations of COPD
por: Wedzicha, Jadwiga A.
Publicado: (2009)

Acute Exacerbation of COPD
por: Pappas, Dominic, et al.
Publicado: (2023)

Effects of Chinese Herbal Medicine on Acute Exacerbations of COPD: A Randomized, Placebo-Controlled Study
por: Li, Jiansheng, et al.
Publicado: (2020)

The Belgian trial with azithromycin for acute COPD exacerbations requiring hospitalization: an investigator-initiated study protocol for a multicenter, randomized, double-blind, placebo-controlled trial
por: Vermeersch, Kristina, et al.
Publicado: (2016)

Treating acute exacerbations of COPD with Chinese herbal medicine to aid antibiotic use reduction (Excalibur): a randomised double-blind, placebo-controlled feasibility trial
por: Willcox, Merlin L., et al.
Publicado: (2023)

Impact of mild exacerbation on COPD symptoms in a Japanese cohort
por: Sato, Minako, et al.
Publicado: (2016)

Effects of YuPingFeng granules on acute exacerbations of COPD: a randomized, placebo-controlled study
por: Ma, Jinfang, et al.
Publicado: (2018)

Lysozyme Inhibitors as Tools for Lysozyme Profiling: Identification and Antibacterial Function of Lysozymes in the Hemolymph of the Blue Mussel
por: Vanderkelen, Lise, et al.
Publicado: (2023)

Tiotropium/olodaterol versus tiotropium in Japanese patients with COPD: results from the DYNAGITO study
por: Ichinose, Masakazu, et al.
Publicado: (2018)

COPD exacerbation: Lost in translation
por: Makris, Demosthenes, et al.
Publicado: (2009)

Lung microbiology and exacerbations in COPD
por: Beasley, Victoria, et al.
Publicado: (2012)

Exacerbation frequency and course of COPD
por: Halpin, David MG, et al.
Publicado: (2012)

Exacerbations in COPD Patients with Bronchiectasis
por: Minov, Jordan, et al.
Publicado: (2017)

Impaired Hemorheology in Exacerbations of COPD
por: Ugurlu, Erhan, et al.
Publicado: (2017)

The airway microbiota and exacerbations of COPD
por: Leiten, Elise Orvedal, et al.
Publicado: (2020)

Models of infection and exacerbations in COPD
por: Papi, Alberto, et al.
Publicado: (2007)

Use of Antibiotics for Exacerbations of COPD
por: Daniels, Johannes M.A., et al.
Publicado: (2017)

Asymmetric Dimethylarginine in COPD Exacerbation
por: Ozkarafakili, Mufide Arzu, et al.
Publicado: (2022)

COPD Exacerbation-Related Pathogens and Previous COPD Treatment
por: Sim, Yun Su, et al.
Publicado: (2022)

The Antibacterial Protein Lysozyme Identified as the Termite Egg Recognition Pheromone
por: Matsuura, Kenji, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_b5jfbrl86astnf85dl58gai1l4