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A CpG-methylation-based assay to predict survival in clear cell renal cell carcinoma

Clear cell renal cell carcinomas (ccRCCs) display divergent clinical behaviours. Molecular markers might improve risk stratification of ccRCC. Here we use, based on genome-wide CpG methylation profiling, a LASSO model to develop a five-CpG-based assay for ccRCC prognosis that can be used with formal...

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Detalles Bibliográficos
Autores principales: Wei, Jin-Huan, Haddad, Ahmed, Wu, Kai-Jie, Zhao, Hong-Wei, Kapur, Payal, Zhang, Zhi-Ling, Zhao, Liang-Yun, Chen, Zhen-Hua, Zhou, Yun-Yun, Zhou, Jian-Cheng, Wang, Bin, Yu, Yan-Hong, Cai, Mu-Yan, Xie, Dan, Liao, Bing, Li, Cai-Xia, Li, Pei-Xing, Wang, Zong-Ren, Zhou, Fang-Jian, Shi, Lei, Liu, Qing-Zuo, Gao, Zhen-Li, He, Da-Lin, Chen, Wei, Hsieh, Jer-Tsong, Li, Quan-Zhen, Margulis, Vitaly, Luo, Jun-Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846314/
https://www.ncbi.nlm.nih.gov/pubmed/26515236
http://dx.doi.org/10.1038/ncomms9699

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