Cargando…

Identification of four new susceptibility loci for testicular germ cell tumour

Genome-wide association studies (GWAS) have identified multiple risk loci for testicular germ cell tumour (TGCT), revealing a polygenic model of disease susceptibility strongly influenced by common variation. To identify additional single-nucleotide polymorphisms (SNPs) associated with TGCT, we cond...

Descripción completa

Detalles Bibliográficos
Autores principales:	Litchfield, Kevin, Holroyd, Amy, Lloyd, Amy, Broderick, Peter, Nsengimana, Jérémie, Eeles, Rosalind, Easton, Douglas F, Dudakia, Darshna, Bishop, D. Timothy, Reid, Alison, Huddart, Robert A., Grotmol, Tom, Wiklund, Fredrik, Shipley, Janet, Houlston, Richard S., Turnbull, Clare
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846317/ https://www.ncbi.nlm.nih.gov/pubmed/26503584 http://dx.doi.org/10.1038/ncomms9690

Ejemplares similares

Validation of loci at 2q14.2 and 15q21.3 as risk factors for testicular cancer
por: Loveday, Chey, et al.
Publicado: (2017)

Whole-exome sequencing reveals the mutational spectrum of testicular germ cell tumours
por: Litchfield, Kevin, et al.
Publicado: (2015)

Rare disruptive mutations in ciliary function genes contribute to testicular cancer susceptibility
por: Litchfield, Kevin, et al.
Publicado: (2016)

Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14
por: Ruark, Elise, et al.
Publicado: (2013)

Testicular microlithiasis as a familial risk factor for testicular germ cell tumour
por: Coffey, J, et al.
Publicado: (2007)

A physical analysis of the Y chromosome shows no additional deletions, other than Gr/Gr, associated with testicular germ cell tumour
por: Linger, R, et al.
Publicado: (2007)

Genomic landscape of platinum resistant and sensitive testicular cancers
por: Loveday, Chey, et al.
Publicado: (2020)

Polygenic susceptibility to testicular cancer: implications for personalised health care
por: Litchfield, Kevin, et al.
Publicado: (2015)

Polygenic susceptibility to testicular cancer: implications for personalised health care
por: Litchfield, Kevin, et al.
Publicado: (2016)

Meta-analysis of five genome-wide association studies identifies multiple new loci associated with testicular germ cell tumor
por: Wang, Zhaoming, et al.
Publicado: (2017)

Identification of 22 susceptibility loci associated with testicular germ cell tumors
por: Pluta, John, et al.
Publicado: (2021)

Quantifying the heritability of testicular germ cell tumour using both population-based and genomic approaches
por: Litchfield, Kevin, et al.
Publicado: (2015)

Chromosomal imbalances associated with carcinoma in situ and associated testicular germ cell tumours of adolescents and adults
por: Summersgill, B, et al.
Publicado: (2001)

Analysis of Genetic Interactions Involving Maternal and Offspring Genotypes at Different Loci: Power Simulation and Application to Testicular Cancer
por: Nsengimana, Jérémie, et al.
Publicado: (2012)

Imaging of testicular germ cell tumours
por: Dalal, P U, et al.
Publicado: (2006)

Recent advances in testicular germ cell tumours
por: Mele, Teresa, et al.
Publicado: (2021)

Molecular cytogenetic analysis of adult testicular germ cell tumours and identification of regions of consensus copy number change.
por: Summersgill, B., et al.
Publicado: (1998)

Microsatellite instability in human testicular germ cell tumours.
por: Huddart, R. A., et al.
Publicado: (1995)

IGF signalling in germ cells and testicular germ cell tumours: roles and therapeutic approaches
por: Selfe, J., et al.
Publicado: (2019)

Meta-analysis identifies four new loci associated with testicular germ cell tumor
por: Chung, Charles C., et al.
Publicado: (2013)

Comment on ‘Prevalence of the metabolic syndrome and cardiovascular disease risk in chemotherapy-treated testicular germ cell tumour survivors'
por: Singhera, M, et al.
Publicado: (2013)

Profiling of the small RNA populations in human testicular germ cell tumors shows global loss of piRNAs
por: Rounge, TB, et al.
Publicado: (2015)

Serum RNA Profiling in the 10-Years Period Prior to Diagnosis of Testicular Germ Cell Tumor
por: Burton, Joshua, et al.
Publicado: (2020)

Somatic mutations of KIT in familial testicular germ cell tumours
por: Rapley, E A, et al.
Publicado: (2004)

IGF1R signalling in testicular germ cell tumour cells impacts on cell survival and acquired cisplatin resistance
por: Selfe, Joanna, et al.
Publicado: (2018)

Tumor loci and their interactions on mouse chromosome 19 that contribute to testicular germ cell tumors
por: Zhu, Rui, et al.
Publicado: (2014)

Genomic copy number and expression patterns in testicular germ cell tumours
por: McIntyre, A, et al.
Publicado: (2007)

Testicular germ cell tumors
por: Albers, Peter
Publicado: (2021)

Multispecies Purification of Testicular Germ Cells
por: Lima, Ana C., et al.
Publicado: (2016)

Immunotherapy in Testicular Germ Cell Tumors
por: Kalavska, Katarina, et al.
Publicado: (2020)

GPER and Testicular Germ Cell Cancer
por: Chevalier, Nicolas, et al.
Publicado: (2021)

Treatment of germ cell testicular cancer
por: Koši Kunac, Ana, et al.
Publicado: (2020)

Genes associated with testicular germ cell tumors and testicular dysgenesis in patients with testicular microlithiasis
por: Dantsev, Ilya S, et al.
Publicado: (2018)

On the Origin of Testicular Germ Cell Tumors: From Gonocytes to Testicular Cancer
por: Baroni, Tiziano, et al.
Publicado: (2019)

Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia
por: Vijayakrishnan, Jayaram, et al.
Publicado: (2018)

Histological Features of Sporadic and Familial Testicular Germ Cell Tumors Compared and Analysis of Age-Related Changes of Histology
por: Stang, Andreas, et al.
Publicado: (2021)

Author Correction: Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia
por: Vijayakrishnan, Jayaram, et al.
Publicado: (2019)

Mediastinal Germ Cell Tumor with Testicular Microlithiasis
por: Mulla, Nasser
Publicado: (2021)

Testicular Germ Cell Tumours and Proprotein Convertases
por: Velado-Eguskiza, Aitziber, et al.
Publicado: (2022)

Genome-wide association study identifies multiple susceptibility loci for glioma
por: Kinnersley, Ben, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_31soi2gkislquaa1ngnksp7qum