Consensus Paper: Cerebellar Development

The development of the mammalian cerebellum is orchestrated by both cell-autonomous programs and inductive environmental influences. Here, we describe the main processes of cerebellar ontogenesis, highlighting the neurogenic strategies used by developing progenitors, the genetic programs involved in...

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Detalles Bibliográficos
Autores principales: Leto, Ketty, Arancillo, Marife, Becker, Esther B. E., Buffo, Annalisa, Chiang, Chin, Ding, Baojin, Dobyns, William B., Dusart, Isabelle, Haldipur, Parthiv, Hatten, Mary E., Hoshino, Mikio, Joyner, Alexandra L., Kano, Masanobu, Kilpatrick, Daniel L., Koibuchi, Noriyuki, Marino, Silvia, Martinez, Salvador, Millen, Kathleen J., Millner, Thomas O., Miyata, Takaki, Parmigiani, Elena, Schilling, Karl, Sekerková, Gabriella, Sillitoe, Roy V., Sotelo, Constantino, Uesaka, Naofumi, Wefers, Annika, Wingate, Richard J. T., Hawkes, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Consensus Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846577/
https://www.ncbi.nlm.nih.gov/pubmed/26439486
http://dx.doi.org/10.1007/s12311-015-0724-2
Descripción
Sumario:The development of the mammalian cerebellum is orchestrated by both cell-autonomous programs and inductive environmental influences. Here, we describe the main processes of cerebellar ontogenesis, highlighting the neurogenic strategies used by developing progenitors, the genetic programs involved in cell fate specification, the progressive changes of structural organization, and some of the better-known abnormalities associated with developmental disorders of the cerebellum.

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