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A systematic review of interventions to improve postpartum retention of women in PMTCT and ART care

INTRODUCTION: The World Health Organization recommends lifelong antiretroviral therapy (ART) for all pregnant and breastfeeding women living with HIV. Effective transitioning from maternal and child health to ART services, and long-term retention in ART care postpartum is crucial to the successful i...

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Autores principales: Geldsetzer, Pascal, Yapa, H Manisha N, Vaikath, Maria, Ogbuoji, Osondu, Fox, Matthew P, Essajee, Shaffiq M, Negussie, Eyerusalem K, Bärnighausen, Till
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International AIDS Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846797/
https://www.ncbi.nlm.nih.gov/pubmed/27118443
http://dx.doi.org/10.7448/IAS.19.1.20679
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author Geldsetzer, Pascal
Yapa, H Manisha N
Vaikath, Maria
Ogbuoji, Osondu
Fox, Matthew P
Essajee, Shaffiq M
Negussie, Eyerusalem K
Bärnighausen, Till
author_facet Geldsetzer, Pascal
Yapa, H Manisha N
Vaikath, Maria
Ogbuoji, Osondu
Fox, Matthew P
Essajee, Shaffiq M
Negussie, Eyerusalem K
Bärnighausen, Till
author_sort Geldsetzer, Pascal
collection PubMed
description INTRODUCTION: The World Health Organization recommends lifelong antiretroviral therapy (ART) for all pregnant and breastfeeding women living with HIV. Effective transitioning from maternal and child health to ART services, and long-term retention in ART care postpartum is crucial to the successful implementation of lifelong ART for pregnant women. This systematic review aims to determine which interventions improve (1) retention within prevention of mother-to-child HIV transmission (PMTCT) programmes after birth, (2) transitioning from PMTCT to general ART programmes in the postpartum period, and (3) retention of postpartum women in general ART programmes. METHODS: We searched Medline, Embase, ISI Web of Knowledge, the regional World Health Organization databases and conference abstracts for data published between 2002 and 2015. The quality of all included studies was assessed using the GRADE criteria. RESULTS AND DISCUSSION: After screening 8324 records, we identified ten studies for inclusion in this review, all of which were from sub-Saharan Africa except for one from the United Kingdom. Two randomized trials found that phone calls and/or text messages improved early (six to ten weeks) postpartum retention in PMTCT. One cluster-randomized trial and three cohort studies found an inconsistent impact of different levels of integration between antenatal care/PMTCT and ART care on postpartum retention. The inconsistent results of the four identified studies on care integration are likely due to low study quality, and heterogeneity in intervention design and outcome measures. Several randomized trials on postpartum retention in HIV care are currently under way. CONCLUSIONS: Overall, the evidence base for interventions to improve postpartum retention in HIV care is weak. Nevertheless, there is some evidence that phone-based interventions can improve retention in PMTCT in the first one to three months postpartum.
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spelling pubmed-48467972016-04-27 A systematic review of interventions to improve postpartum retention of women in PMTCT and ART care Geldsetzer, Pascal Yapa, H Manisha N Vaikath, Maria Ogbuoji, Osondu Fox, Matthew P Essajee, Shaffiq M Negussie, Eyerusalem K Bärnighausen, Till J Int AIDS Soc Review Article INTRODUCTION: The World Health Organization recommends lifelong antiretroviral therapy (ART) for all pregnant and breastfeeding women living with HIV. Effective transitioning from maternal and child health to ART services, and long-term retention in ART care postpartum is crucial to the successful implementation of lifelong ART for pregnant women. This systematic review aims to determine which interventions improve (1) retention within prevention of mother-to-child HIV transmission (PMTCT) programmes after birth, (2) transitioning from PMTCT to general ART programmes in the postpartum period, and (3) retention of postpartum women in general ART programmes. METHODS: We searched Medline, Embase, ISI Web of Knowledge, the regional World Health Organization databases and conference abstracts for data published between 2002 and 2015. The quality of all included studies was assessed using the GRADE criteria. RESULTS AND DISCUSSION: After screening 8324 records, we identified ten studies for inclusion in this review, all of which were from sub-Saharan Africa except for one from the United Kingdom. Two randomized trials found that phone calls and/or text messages improved early (six to ten weeks) postpartum retention in PMTCT. One cluster-randomized trial and three cohort studies found an inconsistent impact of different levels of integration between antenatal care/PMTCT and ART care on postpartum retention. The inconsistent results of the four identified studies on care integration are likely due to low study quality, and heterogeneity in intervention design and outcome measures. Several randomized trials on postpartum retention in HIV care are currently under way. CONCLUSIONS: Overall, the evidence base for interventions to improve postpartum retention in HIV care is weak. Nevertheless, there is some evidence that phone-based interventions can improve retention in PMTCT in the first one to three months postpartum. International AIDS Society 2016-04-25 /pmc/articles/PMC4846797/ /pubmed/27118443 http://dx.doi.org/10.7448/IAS.19.1.20679 Text en © 2016 Geldsetzer P et al; licensee International AIDS Society http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Geldsetzer, Pascal
Yapa, H Manisha N
Vaikath, Maria
Ogbuoji, Osondu
Fox, Matthew P
Essajee, Shaffiq M
Negussie, Eyerusalem K
Bärnighausen, Till
A systematic review of interventions to improve postpartum retention of women in PMTCT and ART care
title A systematic review of interventions to improve postpartum retention of women in PMTCT and ART care
title_full A systematic review of interventions to improve postpartum retention of women in PMTCT and ART care
title_fullStr A systematic review of interventions to improve postpartum retention of women in PMTCT and ART care
title_full_unstemmed A systematic review of interventions to improve postpartum retention of women in PMTCT and ART care
title_short A systematic review of interventions to improve postpartum retention of women in PMTCT and ART care
title_sort systematic review of interventions to improve postpartum retention of women in pmtct and art care
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846797/
https://www.ncbi.nlm.nih.gov/pubmed/27118443
http://dx.doi.org/10.7448/IAS.19.1.20679
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