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Identification and characterization of rabbit ROSA26 for gene knock-in and stable reporter gene expression

The laboratory rabbit has been a valuable model system for human disease studies. To make the rabbit model more amendable to targeted gene knockin and stable gene over-expression, we identified a rabbit orthologue of the mouse Rosa26 locus through genomic sequence homology analysis. Real-time PCR an...

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Detalles Bibliográficos
Autores principales: Yang, Dongshan, Song, Jun, Zhang, Jifeng, Xu, Jie, Zhu, Tianqing, Wang, Zhong, Lai, Liangxue, Chen, Y. Eugene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846827/
https://www.ncbi.nlm.nih.gov/pubmed/27117226
http://dx.doi.org/10.1038/srep25161