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Identification and characterization of rabbit ROSA26 for gene knock-in and stable reporter gene expression
The laboratory rabbit has been a valuable model system for human disease studies. To make the rabbit model more amendable to targeted gene knockin and stable gene over-expression, we identified a rabbit orthologue of the mouse Rosa26 locus through genomic sequence homology analysis. Real-time PCR an...
Autores principales: | Yang, Dongshan, Song, Jun, Zhang, Jifeng, Xu, Jie, Zhu, Tianqing, Wang, Zhong, Lai, Liangxue, Chen, Y. Eugene |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846827/ https://www.ncbi.nlm.nih.gov/pubmed/27117226 http://dx.doi.org/10.1038/srep25161 |
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