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NORE1A Regulates MDM2 Via β-TrCP

Mouse Double Minute 2 Homolog (MDM2) is a key negative regulator of the master tumor suppressor p53. MDM2 regulates p53 on multiple levels, including acting as an ubiquitin ligase for the protein, thereby promoting its degradation by the proteasome. MDM2 is oncogenic and is frequently found to be ov...

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Detalles Bibliográficos
Autores principales:	Schmidt, M. Lee, Calvisi, Diego F., Clark, Geoffrey J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846848/ https://www.ncbi.nlm.nih.gov/pubmed/27023610 http://dx.doi.org/10.3390/cancers8040039

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