Platelet-cytokine Complex Suppresses Tumour Growth by Exploiting Intratumoural Thrombin-dependent Platelet Aggregation

Tumours constitute unique microenvironments where various blood cells and factors are exposed as a result of leaky vasculature. In the present study, we report that thrombin enrichment in B16F10 melanoma led to platelet aggregation, and this property was exploited to administer an anticancer cytokin...

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Detalles Bibliográficos
Autores principales: Li, Yu-Tung, Nishikawa, Tomoyuki, Kaneda, Yasufumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846878/
https://www.ncbi.nlm.nih.gov/pubmed/27117228
http://dx.doi.org/10.1038/srep25077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846878/
https://www.ncbi.nlm.nih.gov/pubmed/27117228
http://dx.doi.org/10.1038/srep25077

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