Accumulation of isolevuglandin-modified protein in normal and fibrotic lung

Protein lysine modification by γ-ketoaldehyde isomers derived from arachidonic acid, termed isolevuglandins (IsoLGs), is emerging as a mechanistic link between pathogenic reactive oxygen species and disease progression. However, the questions of whether covalent modification of proteins by IsoLGs ar...

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Detalles Bibliográficos
Autores principales: Mont, Stacey, Davies, Sean S., Roberts second, L. Jackson, Mernaugh, Raymond L., McDonald, W. Hayes, Segal, Brahm H., Zackert, William, Kropski, Jonathan A., Blackwell, Timothy S., Sekhar, Konjeti R., Galligan, James J., Massion, Pierre P., Marnett, Lawrence J., Travis, Elizabeth L., Freeman, Michael L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847119/
https://www.ncbi.nlm.nih.gov/pubmed/27118599
http://dx.doi.org/10.1038/srep24919

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