Cargando…

Tighter αC-helix–αL16-helix interactions seem to make p38α less prone to activation by autophosphorylation than Hog1

Many eukaryotic protein kinases (EPKs) are autoactivated through autophosphorylation of their activation loop. Mitogen-activated protein (MAP) kinases do not autophosphorylate spontaneously; relying instead upon mitogen-activated protein kinase (MAPK) kinases (MKKs) for their activation loop phospho...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tesker, Masha, Selamat, Sadiduddin Edbe, Beenstock, Jonah, Hayouka, Ruchama, Livnah, Oded, Engelberg, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2016
Materias:	Original Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847175/ https://www.ncbi.nlm.nih.gov/pubmed/26987986 http://dx.doi.org/10.1042/BSR20160020

Ejemplares similares

A conserved arginine within the αC-helix of Erk1/2 is a latch of autoactivation and of oncogenic capabilities
por: Soudah, Nadine, et al.
Publicado: (2023)

Osmostress Induces Autophosphorylation of Hog1 via a C-Terminal Regulatory Region That Is Conserved in p38α
por: Maayan, Inbal, et al.
Publicado: (2012)

Orthogonal functionalisation of α-helix mimetics
por: Barnard, Anna, et al.
Publicado: (2014)

Intrinsically active variants of Erk oncogenically transform cells and disclose unexpected autophosphorylation capability that is independent of TEY phosphorylation
por: Smorodinsky-Atias, Karina, et al.
Publicado: (2016)

A closer look into the α-helix basin
por: Haimov, Boris, et al.
Publicado: (2016)

Isolated α-turn and incipient γ-helix
por: Mir, Fatemeh M., et al.
Publicado: (2019)

Thermodynamic basis of the α-helix and DNA duplex
por: Dragan, A. I., et al.
Publicado: (2021)

H-Bonds in Crambin: Coherence in an α-Helix
por: Nicholson, Stanley, et al.
Publicado: (2023)

Mapping of a N-terminal α-helix domain required for human PINK1 stabilization, Serine228 autophosphorylation and activation in cells
por: Kakade, Poonam, et al.
Publicado: (2022)

An α‐Helix‐Mimicking 12,13‐Helix: Designed α/β/γ‐Foldamers as Selective Inhibitors of Protein–Protein Interactions
por: Grison, Claire M., et al.
Publicado: (2016)

Hog1-induced transcription of RTC3 and HSP12 is robust and occurs in cells lacking Msn2, Msn4, Hot1 and Sko1
por: Bai, Chen, et al.
Publicado: (2020)

Differential Modulation of the Phosphoproteome by the MAP Kinases Isoforms p38α and p38β
por: Melamed Kadosh, Dganit, et al.
Publicado: (2023)

Characterization and sequence prediction of structural variations in α-helix
por: Tendulkar, Ashish V, et al.
Publicado: (2011)

Multi-Facial, Non-Peptidic α-Helix Mimetics
por: Lanning, Maryanna E., et al.
Publicado: (2015)

α-helix formation rate of oligopeptides at subzero temperatures
por: Qin, Zhi-jie, et al.
Publicado: (2014)

HelixGAN a deep-learning methodology for conditional de novo design of α-helix structures
por: Xie, Xuezhi, et al.
Publicado: (2023)

Dynamic Surface Activity by Folding and Unfolding an Amphiphilic α-Helix
por: Jain, Vikas, et al.
Publicado: (2008)

Aromatic Foldamer Helices as α‐Helix Extended Surface Mimetics
por: Zwillinger, Márton, et al.
Publicado: (2020)

N-Terminal Helix-Cap in α-Helix 2 Modulates β-State Misfolding in Rabbit and Hamster Prion Proteins
por: Sweeting, Braden, et al.
Publicado: (2013)

Classification of α-Helical Membrane Proteins Using Predicted Helix Architectures
por: Neumann, Sindy, et al.
Publicado: (2013)

Design, Synthesis, and Conformational Analysis of Oligobenzanilides as Multifacial α-Helix Mimetics
por: Flack, Theo, et al.
Publicado: (2019)

The nematode α-catenin ortholog, HMP1, has an extended α-helix when bound to actin filaments
por: Rangarajan, Erumbi S., et al.
Publicado: (2022)

Solvent-Exposed Salt Bridges Influence the Kinetics of α-Helix Folding and Unfolding
por: Meuzelaar, Heleen, et al.
Publicado: (2014)

Diverse functions of myosin VI elucidated by an isoform-specific α-helix domain
por: Wollscheid, Hans-Peter, et al.
Publicado: (2016)

Mechanical unfolding reveals stable 3-helix intermediates in talin and α-catenin
por: Mykuliak, Vasyl V., et al.
Publicado: (2018)

A glutamine-based single α-helix scaffold to target globular proteins
por: Escobedo, Albert, et al.
Publicado: (2022)

Progesterone modulation of transmembrane helix-helix interactions between the α-subunit of Na/K-ATPase and phospholipid N-methyltransferase in the oocyte plasma membrane
por: Morrill, Gene A, et al.
Publicado: (2010)

The yeast Hot1 transcription factor is critical for activating a single target gene, STL1
por: Bai, Chen, et al.
Publicado: (2015)

An amphipathic α-helix directs palmitoylation of the large intracellular loop of the sodium/calcium exchanger
por: Plain, Fiona, et al.
Publicado: (2017)

An interdomain helix in IRE1α mediates the conformational change required for the sensor's activation
por: Ricci, Daniela, et al.
Publicado: (2021)

Energy Transport along α-Helix Protein Chains: External Drives and Multifractal Analysis
por: Sefidkar, Narmin, et al.
Publicado: (2022)

A perinuclear α-helix with amphipathic features in Brl1 promotes NPC assembly
por: Vitale, Jlenia, et al.
Publicado: (2022)

An inducible amphipathic α-helix mediates subcellular targeting and membrane binding of RPE65
por: Uppal, Sheetal, et al.
Publicado: (2022)

Unique amphipathic α helix drives membrane insertion and enzymatic activity of ATG3
por: Nishimura, Taki, et al.
Publicado: (2023)

Function and conformation analyses of an aspartate substitution of the invariant glycine in the integrin βI domain α1-α1′ helix
por: Guan, Siyu, et al.
Publicado: (2016)

An overview of the basic helix-loop-helix proteins
por: Jones, Susan
Publicado: (2004)

Helix-helix interactions inside lipid bilayers
por: Lemmon, Mark A., et al.
Publicado: (1992)

Helix-helix interaction patterns in membrane proteins
por: Langosch, Dieter, et al.
Publicado: (2011)

Position and Role of the BK Channel α Subunit S0 Helix Inferred from Disulfide Crosslinking
por: Liu, Guoxia, et al.
Publicado: (2008)

Methionine Sulfoxides on Prion Protein Helix-3 Switch on the α-Fold Destabilization Required for Conversion
por: Colombo, Giorgio, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_172jqhvi3pvn338ak8e249huip